Reviewed by Warren Taylor

Barry Sears used obese, and/or diabetic, and/or
hyperinsulemic people as "guinea pigs", to test out his
concepts of CR and anti-aging on human subjects.

In the Biosphere, Roy Walford tested CR in a very
artificial, restricted, and confined manner,
on a small number (8) of human subjects, some of
whom were high cholesterol and over-weight.

But Barry Sears took large numbers (hundreds) of these
quasi-diabetic, hyperinsulemic, syndrome X type
people, and rather than locking them up in a confined
laboratory setting with limited quantities of food,
tested them in an unrestricted, "free-range" existence
in their every-day work environment, to check out and
verify his CR principles on human subjects.

And Barry Sears got the same type of results as Walford.
The same measured CR physiological responses described by Walford!
So I would say that "The Anti-Aging Zone" is one of
the better answers to anyone who complains that CR has
not been tested out on human subjects. Both Walford
and Sears have achieved the expected CR physiological
parameter responses observed in CR animal cohort trials.